Research facilities


Broad range of rat and mouse models:

  • Chemical and electrical models for epileptic seizures and chronic epilepsy
  • Models for Parkinson’s disease: 6-hydroxydopamine and lactacystin model
  • Endothelin-1 model for focal transient cerebral ischemia
  • Several genetic models e.g. astrocyte-specific beta2 adrenergic receptor knockout mouse
  • Microbore ultra-high performance liquid chromatography electrochemical detection for quantification of monoamines


Mouse and rat behavioural unit:

  • Locomotor activity: open field, rotational behaviour (Rotometer), neurological deficit score
  • Spatial memory: Morris water maze for rats and mice; Y maze for mice
  • Anti-depressant-like activity: forced swim test, tail suspension test


Stereotaxic surgery (rat and mouse) and in vivo microdialysis


Telemetry-based 24h video-EEG monitoring units for rodents


Radiotelemetric cardiac monitoring units


PK/PD modelling


Broad range of analytical equipment:

  • Liquid chromatography with electrochemical, fluorescence or ultraviolet detection for the determination of neurotransmitters and drugs
  • Nano ultra-high performance liquid chromatography coupled to tandem mass spectrometry for the determination of neuropeptides and drugs
  • Capillary electrophoresis
  • Size exclusion chromatography


Protein and DNA/RNA electrophoresis


Doppler flowmetry


Cell cultures (growth of neuroviruses, cell infections, quantification) and transfection


Immunological technique (immuno)histochemistry, Western blotting, ELISA


Brain histology, fluorescence microscopy




DNA microarray


Centre for Neurosciences • Vrije Universiteit Brussels • ©2017 • •
Faculty of Medicine & Pharmacie • Laarbeeklaan 103 • 1090 Brussel, BELGIUM • Tel: +32 (2) 477 64 10
Page generated in 0.0006 seconds.  •  Last update: 12 Nov 2015 11:59